Assay Detail
Binding
CHEMBL4882412
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Bovine nasal cartilage (BNC) degradation assay
2
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Tissue | Cartilage tissue |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe BI-4394
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.51 | 7.51 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | ELISA (inhibition of full-length MMP-13-induced cartilage degradation) |
| Assay publication | Assay publication | - | — | PMID: 22017539 |
| Target protein length | Target protein length | - | — | full length |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1939876 | BI 4394 | — | 2 | 7.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1939876 | BI 4394 | IC50 | = | 31.0 | nM | 7.51 |
| CHEMBL1939876 | BI 4394 | IC50 | = | 31.0 | nM | 7.51 |