Assay Detail

CHEMBL4882989

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Binding

FLIPR assay

ChEMBL ↗

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Target

P2Y purinoceptor 14 (CHEMBL4518) ↗

Open DB target context

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P2Y purinoceptor 14 (CHEMBL4518) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target P2Y purinoceptor 14

CHEMBL4518

Anchored from Assay target.

Protein identity P2Y purinoceptor 14

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Pan troglodytes
Confidence	8 — Homologous single protein target
Curated By	Autocuration

Target

P2Y purinoceptor 14 (CHEMBL4518) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe PPTN

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	7.33	9.30

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1800685	PPTN	—	1	9.30
CHEMBL4566600	PPTN-NC	—	1	5.36

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1800685	PPTN	IC50	=	0.5	nM	9.30
CHEMBL4566600	PPTN-NC	IC50	=	4381.0	nM	5.36