Assay Detail
Binding
CHEMBL4883068
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Enzymatic OGA assay
2
Total Activities
2
Compounds Tested
1
Activity Types
4
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe TP-040
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.34 | 7.34 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Production of the fluorescent product was measured every 5 min\nfor 1 h by a SpectraMax Microplate Reader |
| Assay publication | Assay publication | - | — | PMID: 33404239 |
| Target protein length | Target protein length | - | — | full-length |
| Target protein type | Target protein type | - | — | Recombinant human protein from transfected Expi293 cells |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4778870 | TP-040 | — | 1 | 7.34 |
| CHEMBL4748908 | TP-040n | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4778870 | TP-040 | IC50 | = | 46.0 | nM | 7.34 |
| CHEMBL4748908 | TP-040n | IC50 | > | 10000.0 | nM | - |