Assay Detail
Binding
CHEMBL4883070
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In-cell western assay
1
Total Activities
1
Compounds Tested
1
Activity Types
4
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe TP-040
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.35 | 6.35 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Cell-based inhibition of O-GlcNAcase activity: measured increase in the level of O-GlcNAcylated protein\nin cells. |
| Assay publication | Assay publication | - | — | PMID: 33404239 |
| Target protein length | Target protein length | - | — | full-length |
| Target protein type | Target protein type | - | — | human neuroblastoma SH-SY5Y cells |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4778870 | TP-040 | — | 1 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4778870 | TP-040 | EC50 | = | 450.0 | nM | 6.35 |