Assay Detail

CHEMBL4883161

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Binding

MMP inhibition assay (MMP3)

ChEMBL ↗

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Target

Stromelysin-1 (CHEMBL283) ↗

Open DB target context

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Primary target Stromelysin-1

CHEMBL283

Anchored from Assay target.

Protein identity Stromelysin-1

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Stromelysin-1 (CHEMBL283) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe T-26c

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.22	6.22

Assay Parameters

Parameter	Type	Value	Units	Text
Assay publication	Assay publication	-	—	PMID: 25192810

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3337894	T-26c	—	1	6.22

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3337894	T-26c	IC50	=	600.0	nM	6.22