Assay Detail

CHEMBL4883168

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Binding

MMP inhibition assay (MMP13)

ChEMBL ↗

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Target

Collagenase 3 (CHEMBL280) ↗

Open DB target context

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Primary target Collagenase 3

CHEMBL280

Anchored from Assay target.

Protein identity Collagenase 3

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Collagenase 3 (CHEMBL280) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe T-26c

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.41	7.41

Assay Parameters

Parameter	Type	Value	Units	Text
Target protein length	Target protein length	-	—	catalytic domain

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3337895	T-26f	—	1	7.41

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3337895	T-26f	IC50	=	39.0	nM	7.41