Assay Detail

CHEMBL4883186

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Binding

Cell-based assay

ChEMBL ↗

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Target

Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (CHEMBL2321630) ↗

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Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (CHEMBL2321630) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

CHEMBL2321630

Anchored from Assay target.

Protein identity Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (CHEMBL2321630) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe TP-020

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.80	6.80

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4455357	TP-020	—	1	6.80

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4455357	TP-020	IC50	=	160.0	nM	6.80