Assay Detail
Functional
CHEMBL4883702
Review assay metadata, readout intent, target linkage, and publication context from the same page.
CellTiter-Glo Luminescent Cell Viability Assay (BCL-XL dependent cell line H146)
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H146 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Data for DCP probe A-1155463
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.16 | 7.16 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Apoptosis test: 10% HS/ 48 hr |
| Assay publication | Assay publication | - | — | PMID: 25313317 |
| Target protein type | Target protein type | - | — | H146 (BCL-XL dependent cell line) |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3342332 | A-1155463 | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3342332 | A-1155463 | EC50 | = | 70.0 | nM | 7.16 |