Assay Detail
Functional
CHEMBL4883787
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of T cell proliferation in Jurkat cells
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Jurkat |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Dihydroorotate dehydrogenase (quinone), mitochondrial (CHEMBL1966) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe IPP/CNRS-A017
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.70 | 7.70 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | CellTiter-Glo |
| Assay publication | Assay publication | - | — | PMID: 26079043 |
| Target protein type | Target protein type | - | — | Jurkat T lymphocyte cell line |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3589752 | IPP/CNRS-A017 | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3589752 | IPP/CNRS-A017 | IC50 | = | 20.0 | nM | 7.70 |