Assay Detail

CHEMBL4883794

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Binding

Radiometric activity assay, ProQinase (MAPK11)

ChEMBL ↗

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Target

Mitogen-activated protein kinase 11 (CHEMBL3961) ↗

Open DB target context

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Mitogen-activated protein kinase 11 (CHEMBL3961) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Mitogen-activated protein kinase 11

CHEMBL3961

Anchored from Assay target.

Protein identity Mitogen-activated protein kinase 11

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Mitogen-activated protein kinase 11 (CHEMBL3961) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe SR-318

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.50	7.50

Assay Parameters

Parameter	Type	Value	Units	Text
Assay publication	Assay publication	-	—	PMID: 31702918

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4436748	SR-318	—	1	7.50

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4436748	SR-318	IC50	=	32.0	nM	7.50