Assay Detail

CHEMBL4884206

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Binding

Eurofins kinase panel (RPS6KA1)

ChEMBL ↗

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Target

Ribosomal protein S6 kinase alpha-1 (CHEMBL2553) ↗

Open DB target context

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Ribosomal protein S6 kinase alpha-1 (CHEMBL2553) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Ribosomal protein S6 kinase alpha-1

CHEMBL2553

Anchored from Assay target.

Protein identity Ribosomal protein S6 kinase alpha-1

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Ribosomal protein S6 kinase alpha-1 (CHEMBL2553) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe BAY-3827

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.04	8.04

Assay Parameters

Parameter	Type	Value	Units	Text
Compound concentration	Compound concentration	1.0	uM	—

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4580220	BAY-3827	—	1	8.04

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4580220	BAY-3827	IC50	=	9.1	nM	8.04