Assay Detail

CHEMBL4884473

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Binding

Rsk3(h) Eurofins kinase panel

ChEMBL ↗

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Target

Ribosomal protein S6 kinase alpha-2 (CHEMBL3906) ↗

Open DB target context

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Ribosomal protein S6 kinase alpha-2 (CHEMBL3906) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Ribosomal protein S6 kinase alpha-2

CHEMBL3906

Anchored from Assay target.

Protein identity Ribosomal protein S6 kinase alpha-2

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Ribosomal protein S6 kinase alpha-2 (CHEMBL3906) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe BAY-3827

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
% residual kinase activity	1	-	-
IC50	1	7.62	7.62

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4580220	BAY-3827	—	2	7.62

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4580220	BAY-3827	IC50	=	24.0	nM	7.62
CHEMBL4580220	BAY-3827	% residual kinase activity	=	5.0	%	-