Assay Detail

CHEMBL4884582

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Functional

Proliferation assay with EMRK1184 lymphoma cells

ChEMBL ↗

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Target

EMRK1184 (CHEMBL4569158) ↗

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Primary target EMRK1184

CHEMBL4569158

Anchored from Assay target.

Protein identity EMRK1184

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Mus musculus
Cell Type	EMRK1184
Confidence	1 — Organism
Curated By	Autocuration

Target

EMRK1184 (CHEMBL4569158) ↗

Type	CELL-LINE
Organism	Mus musculus

Publication

Data for DCP probe WM-1119

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.60	6.60

Assay Parameters

Parameter	Type	Value	Units	Text
Assay publication	Assay publication	-	—	PMID: 30069049
Target protein type	Target protein type	-	—	Eµ-Myc lymphoma cell line EMRK1184

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4456585	WM-1119	—	1	6.60

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4456585	WM-1119	IC50	=	250.0	nM	6.60