Assay Detail
Binding
CHEMBL4884587
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Enzyme kinetic assay (Reaction Biology) (DDR2)
1
Total Activities
1
Compounds Tested
1
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Discoidin domain-containing receptor 2 (CHEMBL5122) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe SR-302
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.12 | 9.12 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Compound tested in a 10-point dose response IC50 with 3-fold serial dilution starting at 10 µM as highest assay concentration. ATP concentration higher Km(ATP) was chosen. ATP conc. : 5 µM Control compound: Staurosporine (IC50 = 0.38 nM) |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4591082 | SR-302 | — | 1 | 9.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4591082 | SR-302 | IC50 | = | 0.75 | nM | 9.12 |