Assay Detail
Functional
CHEMBL4884601
Review assay metadata, readout intent, target linkage, and publication context from the same page.
HT29 necroptosis assay
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Data for DCP probe TP-030-1
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.32 | 8.89 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 29485864 |
| Target protein type | Target protein type | - | — | human colorectal adenocarcinoma HT-29 cells |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4549667 | TP-030-2 | — | 1 | 8.89 |
| CHEMBL4088216 | TP-030-1 | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4549667 | TP-030-2 | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL4088216 | TP-030-1 | IC50 | = | 18.0 | nM | 7.75 |