Assay Detail
Binding
CHEMBL4885644
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Functional cellular assay: MCP-1 inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | 3T3 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe BAY-6672
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.75 | 7.75 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | profibrotic PGF2α-induced cytokine production |
| Assay publication | Assay publication | - | — | PMID: 32969660 |
| Target protein type | Target protein type | - | — | Lung fibroblasts (mouse 3T3 cells) |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4643852 | BAY-6672 | — | 1 | 7.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4643852 | BAY-6672 | IC50 | = | 18.0 | nM | 7.75 |