Assay Detail
Functional
CHEMBL4885854
Review assay metadata, readout intent, target linkage, and publication context from the same page.
CCR1 cellular Ca2+-flux assay
2
Total Activities
2
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe BAY-3153
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.22 | 8.52 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Calcium transients are detected by Fluo8 Ca-sensitive dye |
| Assay publication | Assay publication | - | — | Slide 13 in BAY-3153 Antagonist for CCR1.pdf |
| Target protein type | Target protein type | - | — | Calcium-optimized stable cell line, #HTS005C |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4638406 | BAY-3153 | — | 1 | 8.52 |
| CHEMBL4647642 | BAY-173 | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4638406 | BAY-3153 | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL4647642 | BAY-173 | IC50 | = | 1200.0 | nM | 5.92 |