Assay Detail
Binding
CHEMBL4886129
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Lactate efflux inhibition assay (RT4)
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Monocarboxylate transporter 2/3 (CHEMBL4802068) ↗| Type | SELECTIVITY GROUP |
| Organism | Homo sapiens |
Publication
Data for DCP probe MSC-4381
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.20 | 6.20 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 34382802 |
| Target protein type | Target protein type | - | — | RT4 (MCT2+/3+) cells |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4802043 | MSC-4381 | — | 1 | 6.20 |
| CHEMBL4802046 | MSC-0516 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4802043 | MSC-4381 | IC50 | = | 638.0 | nM | 6.20 |
| CHEMBL4802046 | MSC-0516 | IC50 | > | 4.0 | nM | - |