Assay Detail

CHEMBL4886864

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Binding

BET mutant TR-FRET assay (BRDT BD2)

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Data for DCP probe GSK973

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	7.60	7.80

Assay Parameters

Parameter	Type	Value	Units	Text
Assay publication	Assay publication	-	—	PMID: 32832027
Target protein length	Target protein length	-	—	BD2

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4637208	GSK973	—	2	7.80

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4637208	GSK973	IC50	=	15.85	nM	7.80
CHEMBL4637208	GSK973	IC50	=	39.81	nM	7.40