Assay Detail

CHEMBL4887032

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Binding

PDE3 (h) CEREP ligand profiling

ChEMBL ↗

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Target

Phosphodiesterase 3 (CHEMBL2094125) ↗

Open DB target context

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Phosphodiesterase 3 (CHEMBL2094125) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Phosphodiesterase 3

CHEMBL2094125

Anchored from Assay target.

Protein identity Phosphodiesterase 3

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	5 — Multiple protein complex / RNA
Curated By	Autocuration

Target

Phosphodiesterase 3 (CHEMBL2094125) ↗

Type	PROTEIN FAMILY
Organism	Homo sapiens

Publication

Data for DCP probe PF-04418948

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Inhibition	1	-	-
IC50	1	5.46	5.46

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3286797	PF-04418948	1.0	2	5.46

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3286797	PF-04418948	IC50	=	3500.0	nM	5.46
CHEMBL3286797	PF-04418948	Inhibition	=	78.0	%	-