Assay Detail
Binding
CHEMBL4887672
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CMA1
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe BI-1942
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.40 | 9.40 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Incubation for 1 h at 28°C; fluorescence measurement |
| Assay publication | Assay publication | - | — | PMID: 23659209 |
| Target protein type | Target protein type | - | — | recombinant human chymase |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3640116 | BI-1942 | — | 1 | 9.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3640116 | BI-1942 | IC50 | = | 0.4 | nM | 9.40 |