Assay Detail
Binding
CHEMBL4888143
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NanoBRET assay (AKT1)
4
Total Activities
2
Compounds Tested
2
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Data for DCP probe Borussertib
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.70 | 7.68 |
| EC50 | 2 | 6.52 | 7.58 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | SGC Frankfurt |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4795065 | Borussertib | — | 2 | 7.68 |
| CHEMBL4802051 | RL2578 | — | 2 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4795065 | Borussertib | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL4795065 | Borussertib | EC50 | = | 26.0 | nM | 7.58 |
| CHEMBL4802051 | RL2578 | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL4802051 | RL2578 | EC50 | = | 3500.0 | nM | 5.46 |