Assay Detail
ADMET
CHEMBL5030108
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Cytotoxicity against human L02 cells assessed as cell growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | L02 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluation of novel covalent inhibitors targeting focal adhesion kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.54 | 5.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5076249 | — | — | 1 | 5.81 |
| CHEMBL5074752 | — | — | 1 | 5.81 |
| CHEMBL5089009 | — | — | 1 | 5.74 |
| CHEMBL5071797 | — | — | 1 | 5.62 |
| CHEMBL5078868 | — | — | 1 | 5.28 |
| CHEMBL458997 | — | — | 1 | 4.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5076249 | — | IC50 | = | 1540.0 | nM | 5.81 |
| CHEMBL5074752 | — | IC50 | = | 1560.0 | nM | 5.81 |
| CHEMBL5089009 | — | IC50 | = | 1840.0 | nM | 5.74 |
| CHEMBL5071797 | — | IC50 | = | 2410.0 | nM | 5.62 |
| CHEMBL5078868 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL458997 | — | IC50 | = | 10760.0 | nM | 4.97 |