Assay Detail

CHEMBL5030256

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of SARS-COV2 main protease using Ac-Abu-Tle-Leu-Gln-AFC as substrate by fluorescence assay

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Severe acute respiratory syndrome coronavirus 2
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Colloidal Aggregators in Biochemical SARS-CoV-2 Repurposing Screens.

O'Donnell HR, Tummino TA, Bardine C, Craik CS, Shoichet BK.
J Med Chem (2021) 64 : 17530 -17539
PubMed 34812616 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	5.32	5.32

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1200712	EVANS BLUE	4.0	1	5.32
CHEMBL46469	ANTHRALIN	2.0	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1200712	EVANS BLUE	IC50	=	4800.0	nM	5.32
CHEMBL46469	ANTHRALIN	IC50	=	-2000.0	nM	-