Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL5030261

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant SARS-COV2 His-tagged S-RBD binding to recombinant human ACE2 expressed in HEK293T cells incubated for 0.5 hrs by alpha screen assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HEK293T
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Angiotensin-converting enzyme 2 (CHEMBL3736)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Colloidal Aggregators in Biochemical SARS-CoV-2 Repurposing Screens.
O'Donnell HR, Tummino TA, Bardine C, Craik CS, Shoichet BK.
J Med Chem (2021) 64 : 17530 -17539
PubMed 34812616 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.00 5.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1360563 HEMATEIN 1 5.00
CHEMBL164 MYRICETIN 1 5.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1360563 HEMATEIN IC50 = 10000.0 nM 5.00
CHEMBL164 MYRICETIN IC50 = 10000.0 nM 5.00