Assay Detail
Functional
CHEMBL5030945
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Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5-FU by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting Colorectal Cancer with Conjugates of a Glucose Transporter Inhibitor and 5-Fluorouracil.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.84 | 4.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5077765 | — | — | 1 | 4.99 |
| CHEMBL5094407 | — | — | 1 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5077765 | — | IC50 | = | 10300.0 | nM | 4.99 |
| CHEMBL5094407 | — | IC50 | = | 21000.0 | nM | 4.68 |