Assay Detail
Functional
CHEMBL5032026
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Antiviral activity against SARS-CoV-2 B.1.1.7 variant assessed as neutralization viral infection in Vero cells by measuring cytopathic effect incubated for 4 days by crystal violet staining based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Computational Design of Potent D-Peptide Inhibitors of SARS-CoV-2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.87 | 5.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5085069 | — | — | 1 | 5.25 |
| CHEMBL5079992 | — | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5085069 | — | IC50 | = | 5570.0 | nM | 5.25 |
| CHEMBL5079992 | — | IC50 | = | 33400.0 | nM | 4.48 |