Assay Detail
Binding
CHEMBL5032064
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Inhibition of Enterococcus faecalis OG1RF YycG autophosphorylation by Kinase-Glo luminescent kinase assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Enterococcus faecalis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Selection and Identification of Novel Antibacterial Agents against Planktonic Growth and Biofilm Formation of <i>Enterococcus faecalis</i>.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.95 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5086652 | — | — | 1 | 5.82 |
| CHEMBL5082462 | — | — | 1 | 5.21 |
| CHEMBL5081308 | — | — | 1 | 5.08 |
| CHEMBL5077746 | — | — | 1 | 4.66 |
| CHEMBL5082238 | — | — | 1 | 4.56 |
| CHEMBL5086076 | — | — | 1 | 4.37 |
| CHEMBL5084154 | — | — | 1 | - |
| CHEMBL5076808 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5086652 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL5082462 | — | IC50 | = | 6100.0 | nM | 5.21 |
| CHEMBL5081308 | — | IC50 | = | 8300.0 | nM | 5.08 |
| CHEMBL5077746 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL5082238 | — | IC50 | = | 27400.0 | nM | 4.56 |
| CHEMBL5086076 | — | IC50 | = | 42900.0 | nM | 4.37 |
| CHEMBL5084154 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL5076808 | — | IC50 | > | 200000.0 | nM | - |