Assay Detail
Functional
CHEMBL5032882
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Enterovirus D68 US/MO/14-18947 harboring 2C protein D183V/D323G drug resistant mutant by CPE assay followed by viral 2C gene sequencing
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | enterovirus D68 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Potent and Broad-Spectrum Pyrazolopyridine-Containing Antivirals against Enteroviruses D68, A71, and Coxsackievirus B3 by Targeting the Viral 2C Protein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.72 | 5.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5079166 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5079166 | — | EC50 | = | 1900.0 | nM | 5.72 |