Assay Detail
Functional
CHEMBL5034111
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human NCI-H526 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H526 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.47 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5078321 | — | — | 1 | 6.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5078321 | — | IC50 | = | 340.0 | nM | 6.47 |