Assay Detail
Functional
CHEMBL5034115
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human SKNBE2 cells assessed as reduction in cell viability after 72 hrs by PrestoBlue Cell Viability assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-N-BE(2) |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery and Synthesis of a Pyrimidine-Based Aurora Kinase Inhibitor to Reduce Levels of MYC Oncoproteins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5078321 | — | — | 1 | 9.00 |
| CHEMBL502124 | — | — | 1 | 9.00 |
| CHEMBL415049 | BARASERTIB | 3.0 | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5078321 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL502124 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL415049 | BARASERTIB | IC50 | = | 1.0 | nM | 9.00 |