Assay Detail
Binding
CHEMBL5035154
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to full-length human LXRalpha by surface plasmon resonance assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
LXR-Mediated Regulation of Marine-Derived Piericidins Aggravates High-Cholesterol Diet-Induced Cholesterol Metabolism Disorder in Mice.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 5.26 | 5.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL272733 | PIERICIDIN A | — | 1 | 5.49 |
| CHEMBL59030 | — | — | 1 | 5.16 |
| CHEMBL4580920 | — | — | 1 | 5.14 |
| CHEMBL4092369 | — | — | 1 | - |
| CHEMBL4464303 | — | — | 1 | - |
| CHEMBL4553875 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL272733 | PIERICIDIN A | Kd | = | 3240.0 | nM | 5.49 |
| CHEMBL59030 | — | Kd | = | 6970.0 | nM | 5.16 |
| CHEMBL4580920 | — | Kd | = | 7220.0 | nM | 5.14 |
| CHEMBL4092369 | — | Kd | = | 3492000000.0 | nM | - |
| CHEMBL4464303 | — | Kd | = | 1373000000.0 | nM | - |
| CHEMBL4553875 | — | Kd | = | 374900000.0 | nM | - |