Assay Detail
Binding
CHEMBL5035789
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to polyamine transport receptor in SRS patient derived SMS mutant human CMS-23916 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Fibroblast |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.48 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5086397 | — | — | 1 | 5.48 |
| CHEMBL23194 | SPERMINE | 0.5 | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5086397 | — | Ki | = | 3280.0 | nM | 5.48 |
| CHEMBL23194 | SPERMINE | Ki | = | 3410.0 | nM | 5.47 |