Assay Detail
Functional
CHEMBL5035927
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Cytotoxicity against human A549 cells after 48 hrs measured by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Aryloxy Pivaloyloxymethyl Prodrugs as Nucleoside Monophosphate Prodrugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.45 | 4.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5086402 | — | — | 1 | 4.46 |
| CHEMBL2046836 | — | — | 1 | 4.44 |
| CHEMBL917 | FLOXURIDINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5086402 | — | IC50 | = | 34460.0 | nM | 4.46 |
| CHEMBL2046836 | — | IC50 | = | 35950.0 | nM | 4.44 |
| CHEMBL917 | FLOXURIDINE | IC50 | > | 100000.0 | nM | - |