Assay Detail
Functional
CHEMBL5035930
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Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Aryloxy Pivaloyloxymethyl Prodrugs as Nucleoside Monophosphate Prodrugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.43 | 4.88 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5081839 | — | — | 1 | 4.88 |
| CHEMBL5086402 | — | — | 1 | 4.45 |
| CHEMBL917 | FLOXURIDINE | 4.0 | 1 | 4.33 |
| CHEMBL2046836 | — | — | 1 | 4.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5081839 | — | IC50 | = | 13110.0 | nM | 4.88 |
| CHEMBL5086402 | — | IC50 | = | 35510.0 | nM | 4.45 |
| CHEMBL917 | FLOXURIDINE | IC50 | = | 46940.0 | nM | 4.33 |
| CHEMBL2046836 | — | IC50 | = | 84760.0 | nM | 4.07 |