Assay Detail
Binding
CHEMBL5036673
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of rat recombinant sEH using CMNPC as substrate incubated for 5 mins by fluorescent based assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Bifunctional epoxide hydrolase 2 (CHEMBL5669) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
From the Design to the <i>In Vivo</i> Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Treatment of Acute Pancreatitis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 9.08 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5081862 | — | — | 1 | 9.40 |
| CHEMBL5084744 | — | — | 1 | 9.40 |
| CHEMBL5093683 | — | — | 1 | 9.40 |
| CHEMBL242459 | — | — | 1 | 8.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5081862 | — | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL5084744 | — | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL5093683 | — | IC50 | = | 0.4 | nM | 9.40 |
| CHEMBL242459 | — | IC50 | = | 8.0 | nM | 8.10 |