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Assay Detail

CHEMBL5037529

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Toxicity in Artemia salina assessed as mortality incubated for 24 hrs in dark by microwell assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Artemia salina
Confidence 1 — Organism
Curated By Autocuration

Target

Artemia salina (CHEMBL612341)
Type ORGANISM
Organism Artemia salina

Publication

Functional Characterization of the Nemertide α Family of Peptide Toxins.
Jacobsson E, Peigneur S, Andersson HS, Laborde Q, Strand M, Tytgat J, Göransson U.
J Nat Prod (2021) 84 : 2121 -2128
PubMed 34445875 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 7 5.85 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5091679 1 6.52
CHEMBL5077579 1 6.40
CHEMBL5093878 1 6.40
CHEMBL5082582 1 5.55
CHEMBL5083412 1 5.54
CHEMBL5091623 1 5.33
CHEMBL5084333 1 5.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5091679 EC50 = 300.0 nM 6.52
CHEMBL5077579 EC50 = 400.0 nM 6.40
CHEMBL5093878 EC50 = 400.0 nM 6.40
CHEMBL5082582 EC50 = 2800.0 nM 5.55
CHEMBL5083412 EC50 = 2900.0 nM 5.54
CHEMBL5091623 EC50 = 4700.0 nM 5.33
CHEMBL5084333 EC50 = 6100.0 nM 5.21