Assay Detail
Binding
CHEMBL5037538
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Modulator activity at german cockroach Nav1 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-electrode voltage clamp assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Blattella germanica |
| Cell Type | Oocyte |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Functional Characterization of the Nemertide α Family of Peptide Toxins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 7.83 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5082582 | — | — | 1 | 8.59 |
| CHEMBL5093878 | — | — | 1 | 8.11 |
| CHEMBL5091679 | — | — | 1 | 8.07 |
| CHEMBL5084333 | — | — | 1 | 8.02 |
| CHEMBL5077579 | — | — | 1 | 7.96 |
| CHEMBL5083412 | — | — | 1 | 7.06 |
| CHEMBL5091623 | — | — | 1 | 7.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5082582 | — | EC50 | = | 2.6 | nM | 8.59 |
| CHEMBL5093878 | — | EC50 | = | 7.8 | nM | 8.11 |
| CHEMBL5091679 | — | EC50 | = | 8.6 | nM | 8.07 |
| CHEMBL5084333 | — | EC50 | = | 9.5 | nM | 8.02 |
| CHEMBL5077579 | — | EC50 | = | 11.1 | nM | 7.96 |
| CHEMBL5083412 | — | EC50 | = | 87.2 | nM | 7.06 |
| CHEMBL5091623 | — | EC50 | = | 97.5 | nM | 7.01 |