Assay Detail
Functional
CHEMBL5039229
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against wild type Human rhinovirus B14 infected in HeLa cells assessed as reduction in virus-induced cytopathic effect incubated for 3 days by MTS/PMS assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | rhinovirus B14 |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.95 | 6.09 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5076204 | — | — | 1 | 6.09 |
| CHEMBL5093941 | — | — | 1 | 6.01 |
| CHEMBL477147 | — | — | 1 | 5.92 |
| CHEMBL5085665 | — | — | 1 | 5.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5076204 | — | EC50 | = | 810.0 | nM | 6.09 |
| CHEMBL5093941 | — | EC50 | = | 980.0 | nM | 6.01 |
| CHEMBL477147 | — | EC50 | = | 1190.0 | nM | 5.92 |
| CHEMBL5085665 | — | EC50 | = | 1650.0 | nM | 5.78 |