Assay Detail
Functional
CHEMBL5039233
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Antiviral activity against Human enterovirus 68 infected in HeLa cells assessed as reduction in virus-induced cytopathic effect incubated for 4 days by MTS/PMS assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | enterovirus D68 |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.05 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5076204 | — | — | 1 | 7.52 |
| CHEMBL477147 | — | — | 1 | 7.10 |
| CHEMBL5085665 | — | — | 1 | 7.00 |
| CHEMBL5093941 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5076204 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL477147 | — | EC50 | = | 80.0 | nM | 7.10 |
| CHEMBL5085665 | — | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL5093941 | — | EC50 | = | 260.0 | nM | 6.58 |