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Assay Detail

CHEMBL5039829

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Functional
Antiproliferative activity against human HepG2 cells incubated for 24 hrs by alamar blue assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HepG2
Confidence 1 — Organism
Curated By Autocuration

Target

HepG2 (CHEMBL395)
Type CELL-LINE
Organism Homo sapiens

Publication

Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Zhou Z, Li Y, Ma X, Cao B, Peng T, Sheng Y, Peng H, Li R, Cao Y, Xi R, Li F, Wang M, Sun H, Zhang G, Zhang H, Hu K, Xiao W, Wang F.
J Med Chem (2021) 64 : 7404 -7421
PubMed 34038111 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.56 4.56

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL463499 1 4.56

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL463499 IC50 = 27260.0 nM 4.56