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Assay Detail

CHEMBL5040264

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-cancer activity against human UACC-62 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type UACC-62
Confidence 1 — Organism
Curated By Autocuration

Target

UACC-62 (CHEMBL614610)
Type CELL-LINE
Organism Homo sapiens

Publication

Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity.
Recio R, Lerena P, Pozo E, Calderón-Montaño JM, Burgos-Morón E, López-Lázaro M, Valdivia V, Pernia Leal M, Mouillac B, Organero JÁ, Khiar N, Fernández I.
J Med Chem (2021) 64 : 10350 -10370
PubMed 34236855 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.50 4.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5083565 1 4.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5083565 IC50 = 31900.0 nM 4.50