Assay Detail
Functional
CHEMBL5040274
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Anti-cancer activity against human A549 cells incubated for 96 hrs by Resazurin assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.56 | 4.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1471 | APREPITANT | 4.0 | 1 | 4.74 |
| CHEMBL5083565 | — | — | 1 | 4.62 |
| CHEMBL5078626 | — | — | 1 | 4.50 |
| CHEMBL5074991 | — | — | 1 | 4.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1471 | APREPITANT | IC50 | = | 18300.0 | nM | 4.74 |
| CHEMBL5083565 | — | IC50 | = | 24200.0 | nM | 4.62 |
| CHEMBL5078626 | — | IC50 | = | 31300.0 | nM | 4.50 |
| CHEMBL5074991 | — | IC50 | = | 40900.0 | nM | 4.39 |