Assay Detail
Binding
CHEMBL5040276
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]SP from human NK1R expressed in U373 MG cells assessed as inhibitory constant incubated for 30 mins by radioligand binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | U373 MG |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 7.65 | 7.65 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5083565 | — | — | 1 | 7.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5083565 | — | Ki | = | 22.4 | nM | 7.65 |