Assay Detail
Binding
CHEMBL5040905
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Inhibition of SE in Candida albicans ATCC SC5314 measured after 30 mins by HPLC analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Candida albicans |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Construction and activity evaluation of novel dual-target (SE/CYP51) anti-fungal agents containing amide naphthyl structure.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.18 | 6.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL626 | NAFTIFINE | 4.0 | 1 | 6.33 |
| CHEMBL5094280 | — | — | 1 | 6.19 |
| CHEMBL5088292 | — | — | 1 | 6.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL626 | NAFTIFINE | IC50 | = | 469.0 | nM | 6.33 |
| CHEMBL5094280 | — | IC50 | = | 650.0 | nM | 6.19 |
| CHEMBL5088292 | — | IC50 | = | 930.0 | nM | 6.03 |