Assay Detail
Functional
CHEMBL5041368
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Cytotoxicity against human HeLa cells assessed as growth inhibition
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dihydrolucilactaene, a Potent Antimalarial Compound from <i>Fusarium</i> sp. RK97-94.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.62 | 8.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 8.37 |
| CHEMBL5074822 | — | — | 1 | 4.85 |
| CHEMBL5078419 | — | — | 1 | 4.67 |
| CHEMBL5072627 | — | — | 1 | 4.60 |
| CHEMBL5081190 | — | — | 1 | - |
| CHEMBL5092772 | — | — | 1 | - |
| CHEMBL5086557 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 4.3 | nM | 8.37 |
| CHEMBL5074822 | — | IC50 | = | 14100.0 | nM | 4.85 |
| CHEMBL5078419 | — | IC50 | = | 21500.0 | nM | 4.67 |
| CHEMBL5072627 | — | IC50 | = | 24900.0 | nM | 4.60 |
| CHEMBL5081190 | — | IC50 | > | 70000.0 | nM | - |
| CHEMBL5092772 | — | IC50 | > | 70000.0 | nM | - |
| CHEMBL5086557 | — | IC50 | > | 70000.0 | nM | - |