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Assay Detail

CHEMBL5041375

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antifungal activity against Pyricularia oryzae kita-1 assessed as growth inhibition
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Pyricularia oryzae
Confidence 1 — Organism
Curated By Autocuration

Target

Pyricularia oryzae (CHEMBL612925)
Type ORGANISM
Organism Pyricularia oryzae

Publication

Dihydrolucilactaene, a Potent Antimalarial Compound from <i>Fusarium</i> sp. RK97-94.
A Abdelhakim I, Bin Mahmud F, Motoyama T, Futamura Y, Takahashi S, Osada H.
J Nat Prod (2022) 85 : 63 -69
PubMed 34949088 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 6 5.99 6.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL267345 AMPHOTERICIN B 4.0 1 6.80
CHEMBL5078419 1 5.17
CHEMBL5074822 1 -
CHEMBL5081190 1 -
CHEMBL5092772 1 -
CHEMBL5072627 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL267345 AMPHOTERICIN B IC50 = 160.0 nM 6.80
CHEMBL5078419 IC50 = 6700.0 nM 5.17
CHEMBL5074822 IC50 > 70000.0 nM -
CHEMBL5081190 IC50 > 70000.0 nM -
CHEMBL5092772 IC50 > 70000.0 nM -
CHEMBL5072627 IC50 > 70000.0 nM -