Assay Detail
Functional
CHEMBL5041377
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Antimalarial activity against wild-type Plasmodium falcipuram 3D7 assessed as growth inhibition
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dihydrolucilactaene, a Potent Antimalarial Compound from <i>Fusarium</i> sp. RK97-94.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.26 | 8.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5078419 | — | — | 1 | 8.82 |
| CHEMBL269671 | ARTEMISININ | 3.0 | 1 | 7.72 |
| CHEMBL5072627 | — | — | 1 | 6.82 |
| CHEMBL5086557 | — | — | 1 | 6.17 |
| CHEMBL5074822 | — | — | 1 | 5.75 |
| CHEMBL5081190 | — | — | 1 | 4.36 |
| CHEMBL5092772 | — | — | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5078419 | — | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL269671 | ARTEMISININ | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL5072627 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL5086557 | — | IC50 | = | 670.0 | nM | 6.17 |
| CHEMBL5074822 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL5081190 | — | IC50 | = | 43900.0 | nM | 4.36 |
| CHEMBL5092772 | — | IC50 | = | 62100.0 | nM | 4.21 |