Assay Detail
Binding
CHEMBL5041650
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Inhibition of Mycobacterium tuberculosis PptT expressed in Escherichia coli incubated for 2 hrs by fluorescence polarization assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
In Vitro and In Vivo Inhibition of the <i>Mycobacterium tuberculosis</i> Phosphopantetheinyl Transferase PptT by Amidinoureas.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.31 | 5.31 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL490129 | SANGUINARIUM CHLORIDE | 2.0 | 1 | 5.31 |
| CHEMBL1208858 | CALMIDAZOLIUM CHLORIDE | — | 1 | 5.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL490129 | SANGUINARIUM CHLORIDE | IC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL1208858 | CALMIDAZOLIUM CHLORIDE | IC50 | = | 4900.0 | nM | 5.31 |