Assay Detail
Binding
CHEMBL5041868
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Inhibition of Glycosidase (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
5-<i>C</i>-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.60 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5088994 | — | — | 1 | 6.70 |
| CHEMBL5085402 | — | — | 1 | 6.10 |
| CHEMBL5028072 | — | — | 1 | 6.00 |
| CHEMBL5091861 | — | — | 1 | 4.92 |
| CHEMBL5082792 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5088994 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL5085402 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL5028072 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL5091861 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL5082792 | — | IC50 | = | 50000.0 | nM | 4.30 |